Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Michelle Longworth
PROVIDER: E-GEOD-74413 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Klebanow Lindsey R LR Peshel Emanuela C EC Schuster Andrew T AT De Kuntal K Sarvepalli Kavitha K Lemieux Madeleine E ME Lenoir Jessica J JJ Moore Adrian W AW McDonald Jocelyn A JA Longworth Michelle S MS
Development (Cambridge, England) 20160617 15
The pattern of the Drosophila melanogaster adult wing is heavily influenced by the expression of proteins that dictate cell fate decisions between intervein and vein during development. dSRF (Blistered) expression in specific regions of the larval wing disc promotes intervein cell fate, whereas EGFR activity promotes vein cell fate. Here, we report that the chromatin-organizing protein CAP-D3 acts to dampen dSRF levels at the anterior/posterior boundary in the larval wing disc, promoting differe ...[more]