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Expression data from WT and Klrc1-/- CD8+ T cells

ABSTRACT: CD8+ T cells and NK cells protect from viral infections by killing virally-infected cells and secreting interferon-g. Several inhibitory receptors limit the magnitude and duration of these anti-viral responses. We used microarrays to assess the transcriptome of ectromelia virus (ECTV) specific CD8+ T cells that genetically lack one such receptor, NKG2A, which is encoded by Klrc1. NaÃ¯ve or ECTV-specific CD8+ T cells were sorted directly into RLT buffer. RNA was then extracted, processed, and hybridized to Affymetrix arrays.

ORGANISM(S): Mus musculus

SUBMITTER: Aaron Rapaport

PROVIDER: E-GEOD-74780 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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