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Effects of vitamin A on ventricular myocardium gene expression [left ventricle]

ABSTRACT: LRAT knockout mice on vitamin A sufficient or deficient diets were compared to age and gender matched wildtype mice on a vitamin A sufficient diet RNA was isolated from the left ventricle of the heart and one array was run for each sample.

ORGANISM(S): Mus musculus

SUBMITTER: Douglas Sawyer

PROVIDER: E-GEOD-74904 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effects of vitamin A deficiency in the postnatal mouse heart: role of hepatic retinoid stores.

Asson-Batres Mary Ann MA Ryzhov Sergey S Tikhomirov Oleg O Duarte Christine W CW Congdon Clare Bates CB Lessard Craig R CR McFarland Samuel S Rochette-Egly Cecile C Tran Truc-Linh TL Galindo Cristi L CL Favreau-Lessard Amanda J AJ Sawyer Douglas B DB

American journal of physiology. Heart and circulatory physiology 20160415 11

To determine whether hepatic depletion of vitamin A (VA) stores has an effect on the postnatal heart, studies were carried out with mice lacking liver retinyl ester stores fed either a VA-sufficient (LRVAS) or VA-deficient (LRVAD) diet (to deplete circulating retinol and extrahepatic stores of retinyl esters). There were no observable differences in the weights or gross morphology of hearts from LRVAS or LRVAD mice relative to sex-matched, age-matched, and genetically matched wild-type (WT) cont ...[more]

PMID: 27084391

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Effects of vitamin A on Ventricular myocardium gene expression [right ventricle]

Project description:LRAT knockout mice on vitamin A sufficient or deficient diets were compared to age-matched wild type mice on a vitamin A sufficient diet RNA was isolated from right ventricle of the heart and one array was run for each sample.

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