Unknown,Transcriptomics,Genomics,Proteomics

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SAGE analysis of wild-type mouse brain regions


ABSTRACT: SAGE libraries generated from various brain regions of 8- to 12-week-old male C57BL/6 mice. Keywords: Micro-dissection, Brain regions, SAGE Sau3A I was used as the anchoring enzyme and Bsmf I as the tagging enzyme. Data are provided after linker removal.

ORGANISM(S): Mus musculus

SUBMITTER: Jean-Marc Elalouf 

PROVIDER: E-GEOD-7594 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models.

Brochier Camille C   Gaillard Marie-Claude MC   Diguet Elsa E   Caudy Nicolas N   Dossat Carole C   Ségurens Béatrice B   Wincker Patrick P   Roze Emmanuel E   Caboche Jocelyne J   Hantraye Philippe P   Brouillet Emmanuel E   Elalouf Jean-Marc JM   de Chaldée Michel M  

Physiological genomics 20080205 2


Using serial analysis of gene expression, we collected quantitative transcriptome data in 11 regions of the adult wild-type mouse brain: the orbital, prelimbic, cingulate, motor, somatosensory, and entorhinal cortices, the caudate-putamen, the nucleus accumbens, the thalamus, the substantia nigra, and the ventral tegmental area. With >1.2 million cDNA tags sequenced, this database is a powerful resource to explore brain functions and disorders. As an illustration, we performed interregional comp  ...[more]

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