17-DMAG treatment in primary CLL B cells
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ABSTRACT: We used microarrays to analyze gene expression following treatment of leukemic B cells with the Hsp90 inhibitor 17-DMAG. Gene expression profiling reveals the role of SOCS3 in cytokine signaling in CLL Primary cells from CLL patients were isolated and treated in vitro with 17-DMAG. Cells were collected for viability, gene expression analysis and cell signaling and migration assays.
ORGANISM(S): Homo sapiens
SUBMITTER: Lianbo Yu
PROVIDER: E-GEOD-76546 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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