Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of rat Mat-Lylu cell line compared to G cell line


ABSTRACT: we analyzed the gene expression profiles of Mat-Lylu cell lines (in duplicate) compared to G cell lines (in duplicate) using Affymetrix tools and dChip software. The objective was to find metastasis-associated genes in prostate cancer, using this in vitro model. Experiment Overall Design: we used Mat_lylu cell line samples (duplicates) as the Experiment group and G cell line samples (duplicates) as control group.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Ismael Reyes 

PROVIDER: E-GEOD-7703 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

DNA microarray analysis reveals metastasis-associated genes in rat prostate cancer cell lines.

Reyes Ismail I   Tiwari Raj R   Geliebter Jan J   Reyes Niradiz N  

Biomedica : revista del Instituto Nacional de Salud 20070601 2


<h4>Introduction</h4>The molecular and cellular mechanisms involved in prostate cancer progression towards a hormone-independent and highly invasive, metastatic phenotype, are not well understood. Cell lines with different metastatic potential, when analyzed by microarray techniques, offer valuable tools for identifying genes associated with the metastatic phenotype.<h4>Objectives</h4>Gene expression profiles were compared for two rat prostate cancer cell lines with differing metastatic abilitie  ...[more]

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