Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Benura Azeroglu
PROVIDER: E-GEOD-77184 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Azeroglu Benura B Mawer Julia S P JS Cockram Charlotte A CA White Martin A MA Hasan A M Mahedi AM Filatenkova Milana M Leach David R F DR
PLoS genetics 20160212 2
Homologous recombination provides a mechanism of DNA double-strand break repair (DSBR) that requires an intact, homologous template for DNA synthesis. When DNA synthesis associated with DSBR is convergent, the broken DNA strands are replaced and repair is accurate. However, if divergent DNA synthesis is established, over-replication of flanking DNA may occur with deleterious consequences. The RecG protein of Escherichia coli is a helicase and translocase that can re-model 3-way and 4-way DNA str ...[more]