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Transcription profiling of mouse heart to examine sex-specific gene expression


ABSTRACT: In this study cDNA microarrays were used to identify genes with sex-biased expression in mouse whole hearts of two age classes (2 months and 8 months of age). Experiment Overall Design: A total of 24 male and female C57BL/6 mice were sacrificed at two and eight months of age, respectively (n=6 per group). Isolated total RNAs were pooled according to sex and age and hybridized on Agilent cDNA microarrays (age-matched, male vs. female or vice versa). Four technical replicates were carried out with exchanged dye-labelled RNA probes (dye-swap) on two of them.

ORGANISM(S): Mus musculus

SUBMITTER: Joerg Isensee 

PROVIDER: E-GEOD-4793 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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