Dataset Information
Gene expression in human glioblastoma specimens
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Amy Heimberger
PROVIDER: E-GEOD-77530 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype.
JCI insight 20160225 2
Glioblastomas are highly infiltrated by diverse immune cells, including microglia, macrophages, and myeloid-derived suppressor cells (MDSCs). Understanding the mechanisms by which glioblastoma-associated myeloid cells (GAMs) undergo metamorphosis into tumor-supportive cells, characterizing the heterogeneity of immune cell phenotypes within glioblastoma subtypes, and discovering new targets can help the design of new efficient immunotherapies. In this study, we performed a comprehensive battery o ...[more]
