T cells from paroxysmal nocturnal hemoglobinuria patients show an altered TNFR signaling pathway

ABSTRACT: In order to identify aberrant molecular mechanisms involved in immune targeting of HSCs in bone marrow, RNA-seq was applied to examine the transcriptome of T cell subsets from PNH patients and healthy controls. RNA seq , 3 PNH patient's T cell subsets (CD4Naive, CD4Memory,CD8Naive, CD8Memory), 3 Healthy T cell subsets (CD4Naive,CD4Memory, CD8Naive, CD8memory)

ORGANISM(S): Homo sapiens

SUBMITTER: Wangmin Qiao 

PROVIDER: E-GEOD-83808 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress