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DNA methylation signatures of parental deprivation in peripheral tissues of male rhesus macaques

ABSTRACT: This study mapped the genome wide DNA methylation changes in whole blood and buccal swab samples of 2 year old male rhesus monkeys subjected to parental deprivation in their first months of life (surrogate peer-reared condition). Equal numbers of control mother-reared (MR) and surrogate peer-reared (SPR) male monkeys whole blood (5 vs 5) and buccal swab samples (3 vs 3) were analyzed by methylated DNA immunoprecipitation (MeDIP) coupled with promoter tiling arrays.

ORGANISM(S): Macaca mulatta

SUBMITTER: Moshe Szyf

PROVIDER: E-GEOD-84020 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Early life adversity alters normal sex-dependent developmental dynamics of DNA methylation in rhesus monkeys

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Leukocyte gene expression in rhesus macaques reared under different conditions

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