Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yi Hong
PROVIDER: E-GEOD-9348 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hong Yi Y Downey Thomas T Eu Kong Weng KW Koh Poh Koon PK Cheah Peh Yean PY
Clinical & experimental metastasis 20100209 2
Metastasis is the major cause of cancer mortality. We aimed to find a metastasis-prone signature for early stage mismatch-repair proficient sporadic colorectal cancer (CRC) patients for better prognosis and informed use of adjuvant chemotherapy. The genome-wide expression profiles of 82 age-, ethnicity- and tissue-matched patients and healthy controls were analyzed using the Affymetrix U133 Plus 2 array. Metastasis-negative patients have 5 years or more of follow-up. A 10 x 10 two-level nested c ...[more]