Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Yukako Oma
PROVIDER: E-GEOD-9421 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Shimada Kenji K Oma Yukako Y Schleker Thomas T Kugou Kazuto K Ohta Kunihiro K Harata Masahiko M Gasser Susan M SM
Current biology : CB 20080410 8
<h4>Background</h4>Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires actin-related proteins, Arp4, Arp5 and Arp8, as well as two RuvB-like DNA helicase subunits. Budding yeast mutants deficient for Ino80 function are not only hypersensitive to reagents that induce ...[more]