Unknown,Transcriptomics,Genomics,Proteomics

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Ino80 chromatin remodeling complex promotes recovery of stalled replication forks


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE9233: Genome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae GSE9420: Genome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Yukako Oma 

PROVIDER: E-GEOD-9421 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks.

Shimada Kenji K   Oma Yukako Y   Schleker Thomas T   Kugou Kazuto K   Ohta Kunihiro K   Harata Masahiko M   Gasser Susan M SM  

Current biology : CB 20080410 8


<h4>Background</h4>Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires actin-related proteins, Arp4, Arp5 and Arp8, as well as two RuvB-like DNA helicase subunits. Budding yeast mutants deficient for Ino80 function are not only hypersensitive to reagents that induce  ...[more]

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