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Testes gene expression and aging

ABSTRACT: 14 bp RsaI SAGE analysis of testes from 3 month and 29 month BDF1 mice, and 14 month SAMP1 mice. Keywords: other

ORGANISM(S): Mus musculus

SUBMITTER: Junjie Yao

PROVIDER: E-GEOD-950 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Mouse testis transcriptome revealed using serial analysis of gene expression.

Yao Junjie J Chiba Takuya T Sakai Jun J Hirose Kunitaka K Yamamoto Mikio M Hada Akiyuki A Kuramoto Kazunao K Higuchi Keiichi K Mori Masayuki M

Mammalian genome : official journal of the International Mammalian Genome Society 20040601 6

We applied serial analysis of gene expression (SAGE) to the mouse testis to reveal the global gene expression profile and to identify senescence-dependent changes in that profile. A total of 61,929 SAGE tags, including 19,323 unique tags, were obtained from 3- and 29-month-old BDF1 mice and 14-month-old SAMP1 mice. Genes highly expressed in the testis included those associated with spermatogenesis, protein metabolism, energy metabolism, growth and differentiation, and signal transduction. Testes ...[more]

PMID: 15181536

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