Ontology highlight
ABSTRACT:
ORGANISM(S): Plasmodium falciparum 3D7
SUBMITTER: Laurence Florens
PROVIDER: E-GEOD-92 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Florens Laurence L Washburn Michael P MP Raine J Dale JD Anthony Robert M RM Grainger Munira M Haynes J David JD Moch J Kathleen JK Muster Nemone N Sacci John B JB Tabb David L DL Witney Adam A AA Wolters Dirk D Wu Yimin Y Gardner Malcolm J MJ Holder Anthony A AA Sinden Robert E RE Yates John R JR Carucci Daniel J DJ
Nature 20021001 6906
The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which to conduct comparative proteomics studies of this human pathogen. Here, we applied a high-throughput proteomics approach to identify new potential drug and vaccine targets and to better understand the biology of this complex protozoan parasite. We characterized four stages of the parasite life cycle (sporozoites, merozoites, trophozoites and gametocytes) by multidimensional protein identification technology. F ...[more]