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Transcription profiling of Xenopus hybrid sex reversal experiment

ABSTRACT: This SuperSeries is composed of the following subset Series:; GSE9504: Expression data from hybrid female Xenopus sex reversal experiment; GSE9505: Expression data from hybrid male Xenopus sex reversal experiment Experiment Overall Design: Refer to individual Series

ORGANISM(S): Xenopus laevis x Xenopus muelleri

SUBMITTER: John Malone

PROVIDER: E-GEOD-9507 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Physiological sex predicts hybrid sterility regardless of genotype.

Malone John H JH Michalak P P

Science (New York, N.Y.) 20080101 5859

Reproductive isolation between biological species is characterized by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctional effects of hybridization. It has been hypothesized that, in addition to X-linked recessive genes, Haldane's rule also reflects the faster evolution of genes related to male reproduction (faster-male evolution). We used sex-reversed hybrid Xenopus to test faster-male evolution by examining the fertility of sex-reversed individuals ...[more]

PMID: 18174434

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