Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Marion Horsch
PROVIDER: E-GEOD-9999 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Söker Torben T Dalke Claudia C Puk Oliver O Floss Thomas T Becker Lore L Bolle Ines I Favor Jack J Hans Wolfgang W Hölter Sabine M SM Horsch Marion M Kallnik Magdalena M Kling Eva E Moerth Corinna C Schrewe Anja A Stigloher Christian C Topp Stefanie S Gailus-Durner Valerie V Naton Beatrix B Beckers Johannes J Fuchs Helmut H Ivandic Boris B Klopstock Thomas T Schulz Holger H Wolf Eckhard E Wurst Wolfgang W Bally-Cuif Laure L de Angelis Martin Hrabé MH Graw Jochen J
BMC developmental biology 20081222
<h4>Background</h4>In Drosophila, mutations in the gene eyes absent (eya) lead to severe defects in eye development. The functions of its mammalian orthologs Eya1-4 are only partially understood and no mouse model exists for Eya3. Therefore, we characterized the phenotype of a new Eya3 knockout mouse mutant.<h4>Results</h4>Expression analysis of Eya3 by in-situ hybridizations and beta-Gal-staining of Eya3 mutant mice revealed abundant expression of the gene throughout development, e.g. in brain, ...[more]