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Transcription profiling of human carotids with advanced atherosclerosis obtained at autopsy and at vascular surgery

ABSTRACT: The microarray gene expression profiles of human carotids with advanced atherosclerosis obtained at autopsy (n=4) were compared with those obained at vascular surgery (n=3).

INSTRUMENT(S): DNA Microarray Scanner BA [Agilent Technologies]

ORGANISM(S): Homo sapiens

DISEASE(S): advanced atherosclerosis

SUBMITTER: Oscar Volger

PROVIDER: E-MEXP-1004 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery.

Sluimer Judith C JC Kisters Natasja N Cleutjens Kitty B KB Volger Oscar L OL Horrevoets Anton J AJ van den Akker Luc H LH Bijnens Ann-Pascale J AP Daemen Mat J MJ

Physiological genomics 20070522 3

Since inclusion of atherosclerotic tissues from different sources is often indispensable to study the full atherogenic spectrum, we investigated to what extent the expression profiles of advanced, stable atherosclerotic lesions obtained during autopsy and surgery are comparable. The gene expression profiles of human carotids with advanced atherosclerosis obtained at autopsy and at vascular surgery were studied by microarray analysis. Expression analysis was performed both at the single gene (Ros ...[more]

PMID: 17519360

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