Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lizhong Hao
PROVIDER: E-MEXP-1130 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Taylor Jennifer M JM Street Teresa L TL Hao Lizhong L Copley Richard R Taylor Martin S MS Hayden Patrick J PJ Stolper Gina G Mott Richard R Hein Jotun J Moffatt Miriam F MF Cookson William O C M WO
PloS one 20091030 10
The mammalian epidermis is a continually renewing structure that provides the interface between the organism and an innately hostile environment. The keratinocyte is its principal cell. Keratinocyte proteins form a physical epithelial barrier, protect against microbial damage, and prepare immune responses to danger. Epithelial immunity is disordered in many common diseases and disordered epithelial differentiation underlies many cancers. In order to identify the genes that mediate epithelial dev ...[more]