Transcription profiling of yeast deletion strain and the isogenic wild type strainA
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Tim Hughes
PROVIDER: E-MEXP-12 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A panoramic view of yeast noncoding RNA processing.
Peng Wen Tao WT Robinson Mark D MD Mnaimneh Sanie S Krogan Nevan J NJ Cagney Gerard G Morris Quaid Q Davierwala Armaity P AP Grigull Jörg J Yang Xueqi X Zhang Wen W Mitsakakis Nicholas N Ryan Owen W OW Datta Nira N Jojic Vladimir V Pal Chris C Canadien Veronica V Richards Dawn D Beattie Bryan B Wu Lani F LF Altschuler Steven J SJ Roweis Sam S Frey Brendan J BJ Emili Andrew A Greenblatt Jack F JF Hughes Timothy R TR
Cell 20030601 7
Predictive analysis using publicly available yeast functional genomics and proteomics data suggests that many more proteins may be involved in biogenesis of ribonucleoproteins than are currently known. Using a microarray that monitors abundance and processing of noncoding RNAs, we analyzed 468 yeast strains carrying mutations in protein-coding genes, most of which have not previously been associated with RNA or RNP synthesis. Many strains mutated in uncharacterized genes displayed aberrant nonco ...[more]
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