Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Beat Schafer
PROVIDER: E-MEXP-122 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Leukemia 20041001 10
Several studies involving identical twins with concordant leukemia and retrospective scrutiny of archived neonatal blood spots have shown that the TEL-AML1 fusion gene in childhood acute lymphoblastic leukemia (ALL) frequently arises before birth. A prenatal origin of childhood leukemia was further supported by the detection of clonotypic immunoglobulin gene rearrangements on neonatal blood spots of children with various other subtypes of ALL. However, no comprehensive study is available linking ...[more]