Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of leukemic cells of monozygotic twins


ABSTRACT: We established gene expression profiles of diagnostic bone marrow samples of monozygotic twins with acute lymphoblastic leukemia. We established technical duplicates for each twin.

ORGANISM(S): Homo sapiens

SUBMITTER: Beat Schafer 

PROVIDER: E-MEXP-122 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Prenatal origin of separate evolution of leukemia in identical twins.

Teuffel O O   Betts D R DR   Dettling M M   Schaub R R   Schäfer B W BW   Niggli F K FK  

Leukemia 20041001 10


Several studies involving identical twins with concordant leukemia and retrospective scrutiny of archived neonatal blood spots have shown that the TEL-AML1 fusion gene in childhood acute lymphoblastic leukemia (ALL) frequently arises before birth. A prenatal origin of childhood leukemia was further supported by the detection of clonotypic immunoglobulin gene rearrangements on neonatal blood spots of children with various other subtypes of ALL. However, no comprehensive study is available linking  ...[more]

Similar Datasets

2004-06-28 | E-MEXP-120 | biostudies-arrayexpress
2012-12-27 | GSE43141 | GEO
2012-10-20 | GSE33477 | GEO
2012-12-27 | E-GEOD-43141 | biostudies-arrayexpress
2014-03-24 | E-GEOD-44742 | biostudies-arrayexpress
2014-03-24 | E-GEOD-53822 | biostudies-arrayexpress
2007-12-11 | GSE9559 | GEO
2013-03-06 | GSE42700 | GEO
2014-03-24 | GSE44742 | GEO
2014-03-24 | GSE53822 | GEO