Dataset Information
Transcription profiling of Plasmodium 3D7AH1S2 and 3D7S8.4 at three different stages of intraerythrocytic cycle: ring, trophozite and schizont stage
Ontology highlight
ABSTRACT:
ORGANISM(S): Plasmodium falciparum
SUBMITTER: Bobo Mok
PROVIDER: E-MEXP-128 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Comparative transcriptomal analysis of isogenic Plasmodium falciparum clones of distinct antigenic and adhesive phenotypes.
Molecular and biochemical parasitology 20061204 2
Antigenic variation is a survival mechanism developed by the malaria parasite Plasmodium falciparum in order to allow for the establishment of a chronic infection. Here we have studied clonal differences in the transcriptomes of two isogenic P. falciparum clones (3D7S8.4 and 3D7AH1S2) of distinct adhesive and antigenic phenotypes employing a P. falciparum 70-mer oligonucleotide microarray. Fifteen transcripts were highly differentially expressed (greater than a 5-fold change) with five transcrip ...[more]
