Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of C. elegans aging in 5 individuals of each age (4,9,14,or 19 days) of each of two genotypes (N2 or daf-2)N2 daf-2

ABSTRACT: Gene expression profiles were generated for 4-5 individuals of each age (4,9,14,or 19 days) of each of two genotypes (N2 or daf-2)

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Simon Melov

PROVIDER: E-MEXP-138 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray analysis of gene expression with age in individual nematodes.

Golden Tamara R TR Melov Simon S

Aging cell 20040601 3

We compare the aging of wild-type and long-lived C. elegans by gene expression profiling of individual nematodes. Using a custom cDNA array, we have characterized the gene expression of 4-5 individuals at 4 distinct ages throughout the adult lifespan of wild-type N2 nematodes, and at the same ages for individuals of the long-lived strain daf-2(e1370). Using statistical tools developed for microarray data analysis, we identify genes that differentiate aging N2 from aging daf-2, as well as classes ...[more]

PMID: 15153179

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Dataset Information

Transcription profiling of C. elegans aging in 5 individuals of each age (4,9,14,or 19 days) of each of two genotypes (N2 or daf-2)N2 daf-2

Publications

Microarray analysis of gene expression with age in individual nematodes.

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