Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MicroRNA profiling of liver from vitellogenic and non-vitellogenic zebrafish females


ABSTRACT: Liver samples were collected from zebrafish females (3 months old). Vitellogenic females were maintained under conditions of 14 h light: 10 h dark. Non-vitellogenic females were obtained by exposing females to 6 h light/18 h dark regime.

ORGANISM(S): Danio rerio

SUBMITTER: Amit Cohen 

PROVIDER: E-MEXP-1572 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Estrogen regulation of microRNAs, target genes, and microRNA expression associated with vitellogenesis in the zebrafish.

Cohen Amit A   Smith Yoav Y  

Zebrafish 20130615 5


Estrogen is a steroid hormone that has been implicated in a variety of cellular and physiological processes and in the development of diseases such as cancer. Here we show a remarkable widespread microRNA (miRNA) downregulation in the zebrafish (Danio rerio) liver following 17β-estradiol (E2) treatment. This unique miRNA expression signature in the fish liver was further supported by a combination of computational predictions with gene expression microarray data, showing a significant bias towar  ...[more]

Similar Datasets

2009-05-22 | E-MEXP-2183 | biostudies-arrayexpress
2007-12-30 | E-MEXP-1147 | biostudies-arrayexpress
2009-08-01 | E-MEXP-2079 | biostudies-arrayexpress
2009-08-01 | E-MEXP-2080 | biostudies-arrayexpress
2009-05-26 | E-MEXP-1683 | biostudies-arrayexpress
2012-01-13 | E-GEOD-35074 | biostudies-arrayexpress
2018-01-12 | E-MTAB-3220 | biostudies-arrayexpress
2013-10-31 | E-GEOD-19768 | biostudies-arrayexpress
2009-05-11 | E-MEXP-2110 | biostudies-arrayexpress
2010-06-21 | E-GEOD-17336 | biostudies-arrayexpress