Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
DISEASE(S): normal
SUBMITTER: Eric Prina
PROVIDER: E-MEXP-1595 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Osorio y Fortéa José J de La Llave Emilie E Regnault Béatrice B Coppée Jean-Yves JY Milon Geneviève G Lang Thierry T Prina Eric E
BMC genomics 20090320
<h4>Background</h4>Mammal macrophages (MPhi) display a wide range of functions which contribute to surveying and maintaining tissue integrity. One such function is phagocytosis, a process known to be subverted by parasites like Leishmania (L). Indeed, the intracellular development of L. amazonensis amastigote relies on the biogenesis and dynamic remodelling of a phagolysosome, termed the parasitophorous vacuole, primarily within dermal MPhi.<h4>Results</h4>Using BALB/c mouse bone marrow-derived ...[more]