Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Pichia pastoris strain GS115 transformed with the empty vector pGAPHIS or consitutively overproducing the activated form of S. cerevisiae Hac1


ABSTRACT: Strain GS115 transformed with the empty vector pGAPHIS (a histidine prototrophic isogenic strain of GS115) was compared to Strain GS115 HAC1, constitutively overproducing the activated form of S. cerevisiae Hac1

ORGANISM(S): Pichia pastoris

SUBMITTER: Alexandra Graf 

PROVIDER: E-MEXP-1616 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays.

Graf Alexandra A   Gasser Brigitte B   Dragosits Martin M   Sauer Michael M   Leparc Germán G GG   Tüchler Thomas T   Kreil David P DP   Mattanovich Diethard D  

BMC genomics 20080819


<h4>Background</h4>DNA Microarrays are regarded as a valuable tool for basic and applied research in microbiology. However, for many industrially important microorganisms the lack of commercially available microarrays still hampers physiological research. Exemplarily, our understanding of protein folding and secretion in the yeast Pichia pastoris is presently widely dependent on conclusions drawn from analogies to Saccharomyces cerevisiae. To close this gap for a yeast species employed for its h  ...[more]

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