Ontology highlight
ABSTRACT:
them with those of healthy individuals. Also compare the transcriptome profiles of the closely related Systemic lupus Erythematosus autoimmune disorder with the same profiles from healthy individuals
ORGANISM(S): Homo sapiens
SUBMITTER: Irantzu Bernales
PROVIDER: E-MEXP-1635 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Genes and immunity 20071025 1
Primary antiphospholipid syndrome (PAPS) is a systemic autoimmune disorder characterized by thromboembolic episodes and pregnant morbidity with an increasing clinical importance. To gain insight into the pathogenesis of PAPS, we have investigated the gene expression profiles that characterize peripheral blood mononuclear cells derived from PAPS patients. We show that the transcriptional activity of genes involved in innate immune responses, such as toll-like receptor 8 and CD14, as well as downs ...[more]