Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Giovanni Gaudino
PROVIDER: E-MEXP-1700 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
American journal of respiratory cell and molecular biology 20090605 3
MicroRNAs (miRNAs) post-transcriptionally regulate the expression of target genes, and may behave as oncogenes or tumor suppressors. Human malignant mesothelioma is an asbestos-related cancer, with poor prognosis and low median survival. Here we report, for the first time, a cross-evaluation of miRNA expression in mesothelioma (MPP-89, REN) and human mesothelial cells (HMC-telomerase reverse transcriptase). Microarray profiling, confirmed by real-time quantitative RT-PCR, revealed a differential ...[more]