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Comparative genomic hybridization of twenty four Salmonella enteritidis strains from six phage types

ABSTRACT: In this study differences at the genetic level of 24 S. Enteritidis strains from six phage types were compared using Comparative Genomic Hybridisation (CGH) DNA microarrays to determine why some certain phage types are 'less successful' in causing human infection.

ORGANISM(S): Salmonella typhimurium

SUBMITTER: Zhensheng Pan

PROVIDER: E-MEXP-1720 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Identification of genetic and phenotypic differences associated with prevalent and non-prevalent Salmonella Enteritidis phage types: analysis of variation in amino acid transport.

Pan Zhensheng Z Carter Ben B Núñez-García Javier J AbuOun Manal M Fookes María M Ivens Al A Woodward Martin J MJ Anjum Muna F MF

Microbiology (Reading, England) 20090702 Pt 10

In this study, differences at the genetic level of 37 Salmonella Enteritidis strains from five phage types (PTs) were compared using comparative genomic hybridization (CGH) to assess differences between PTs. There were approximately 400 genes that differentiated prevalent (4, 6, 8 and 13a) and sporadic (11) PTs, of which 35 were unique to prevalent PTs, including six plasmid-borne genes, pefA, B, C, D, srgC and rck, and four chromosomal genes encoding putative amino acid transporters. Phenotype ...[more]

PMID: 19574306

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