Dataset Information
Transcription profiling of yeast W303 cells at multiple time points during meiosis
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Michael klutstein
PROVIDER: E-MEXP-1781 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Combination of genomic approaches with functional genetic experiments reveals two modes of repression of yeast middle-phase meiosis genes.
BMC genomics 20100817
<h4>Background</h4>Regulation of meiosis and sporulation in Saccharomyces cerevisiae is a model for a highly regulated developmental process. Meiosis middle phase transcriptional regulation is governed by two transcription factors: the activator Ndt80 and the repressor Sum1. It has been suggested that the competition between Ndt80 and Sum1 determines the temporal expression of their targets during middle meiosis.<h4>Results</h4>Using a combination of ChIP-on-chip and expression profiling, we cha ...[more]
