Dataset Information
Transcription profiling of E. coli strain MC4100 in comparison to its otherwise isogenic ycgE::cat derivative to identify YcgE dependent genes
Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Natalia Tschowri
PROVIDER: E-MEXP-1872 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli.
Genes & development 20090201 4
The blue light using FAD (BLUF)-EAL protein YcgF is a known blue-light sensor of Escherichia coli, but its direct regulatory output and physiological function have remained unknown. Here, we demonstrate that unlike other EAL domain proteins, YcgF does not degrade the signaling molecule c-di-GMP, but directly binds to and releases the MerR-like repressor YcgE from its operator DNA upon blue-light irradiation. As a consequence, a distinct regulon of eight small proteins (of 71-126 amino acids) is ...[more]
