Ontology highlight
ABSTRACT:
ORGANISM(S): Bacillus cereus
SUBMITTER: Roger Simm
PROVIDER: E-MEXP-3537 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20120516 5
Transcriptional profiling highlighted a subset of genes encoding putative multidrug transporters in the pathogen Bacillus cereus that were up-regulated during stress produced by bile salts. One of these multidrug transporters (BC4707) was selected for investigation. Functional characterization of the BC4707 protein in Escherichia coli revealed a role in the energized efflux of xenobiotics. Phenotypic analyses after inactivation of the gene bc4707 in Bacillus cereus ATCC14579 suggested a more spe ...[more]