Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human mesenchymal stem cells exposed to different profiles of fluid flow-induced shear stress to investigate the effects on the MARK signaling pathway

ABSTRACT: Effect of different profiles of fluid flow-induced shear stress application on MAPK pathway gene expression in human mesenchymal stem cells

ORGANISM(S): Homo sapiens

SUBMITTER: John Glossop

PROVIDER: E-MEXP-1923 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Effect of fluid flow-induced shear stress on human mesenchymal stem cells: differential gene expression of IL1B and MAP3K8 in MAPK signaling.

Glossop John R JR Cartmell Sarah H SH

Gene expression patterns : GEP 20090120 5

Human bone marrow-derived mesenchymal stem cells (MSCs) can differentiate into numerous cell lineages, making them ideal for tissue engineering. Mechanical forces and mechanotransduction are important factors influencing cell responses, although such data are limited for MSCs. We investigated the effect of different profiles of fluid flow-induced shear stress on mitogen-activated protein kinase (MAPK) signaling pathway gene expression in MSCs using DNA microarray and quantitative real-time rever ...[more]

PMID: 19272346

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Dataset Information

Transcription profiling of human mesenchymal stem cells exposed to different profiles of fluid flow-induced shear stress to investigate the effects on the MARK signaling pathway

Publications

Effect of fluid flow-induced shear stress on human mesenchymal stem cells: differential gene expression of IL1B and MAP3K8 in MAPK signaling.

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