Ontology highlight
ABSTRACT:
To identify non-specific or inconsistent hybridizations, 4 arrays were hybridized to cDNA from different populations of uninfected CrFK cells, and 2 arrays to cells exposed to "spent" (culture media isolated from cells grown normally in culture for 3-7 days) culture media. Data from uninfected cells were analyzed individually, and in combination with data from media-treated cells, as described above.
ORGANISM(S): Felis catus
SUBMITTER: Ryan J Dowling
PROVIDER: E-MEXP-205 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
The Journal of general virology 20050801 Pt 8
Infection of cats with Feline immunodeficiency virus (FIV) is an important model for understanding comparative lentivirus biology. In vivo, FIV infects lymphocytes and monocyte/macrophages, but in vitro infection is commonly investigated in epithelial Crandell-Reese Feline Kidney (CRFK) cells. In this study, the transcriptional responses of CRFK cells and primary lymphocytes to infection with FIV 34TF, a cloned subtype A virus, and FIV USgaB01, a biological subtype B isolate, were determined. Re ...[more]