Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of cat CrFK cells grown under steady state conditions


ABSTRACT: Characterization of CrFK Cells Grown Under Steady State Conditions:

To identify non-specific or inconsistent hybridizations, 4 arrays were hybridized to cDNA from different populations of uninfected CrFK cells, and 2 arrays to cells exposed to "spent" (culture media isolated from cells grown normally in culture for 3-7 days) culture media. Data from uninfected cells were analyzed individually, and in combination with data from media-treated cells, as described above.

ORGANISM(S): Felis catus

SUBMITTER: Ryan J Dowling 

PROVIDER: E-MEXP-205 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene-expression changes induced by Feline immunodeficiency virus infection differ in epithelial cells and lymphocytes.

Dowling R J O RJO   Bienzle D D  

The Journal of general virology 20050801 Pt 8


Infection of cats with Feline immunodeficiency virus (FIV) is an important model for understanding comparative lentivirus biology. In vivo, FIV infects lymphocytes and monocyte/macrophages, but in vitro infection is commonly investigated in epithelial Crandell-Reese Feline Kidney (CRFK) cells. In this study, the transcriptional responses of CRFK cells and primary lymphocytes to infection with FIV 34TF, a cloned subtype A virus, and FIV USgaB01, a biological subtype B isolate, were determined. Re  ...[more]

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