Ontology highlight
ABSTRACT:
ORGANISM(S): Schizosaccharomyces pombe
SUBMITTER: Adam Rosebrock
PROVIDER: E-MEXP-208 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
BMC biology 20050517
<h4>Background</h4>PCI/MPN domain protein complexes comprise the 19S proteasome lid, the COP9 signalosome (CSN), and eukaryotic translation initiation factor 3 (eIF3). The eIF3 complex is thought to be composed of essential core subunits required for global protein synthesis and non-essential subunits that may modulate mRNA specificity. Interactions of unclear significance were reported between eIF3 subunits and PCI proteins contained in the CSN.<h4>Results</h4>Here, we report the unexpected fin ...[more]