Ontology highlight
ABSTRACT:
ORGANISM(S): Zea mays
SUBMITTER: Carlos Vicient
PROVIDER: E-MEXP-2702 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Sánchez-Pons Nuria N Irar Sami S García-Muniz Nora N Vicient Carlos M CM
BMC plant biology 20110519 1
<h4>Background</h4>Camptothecin is a plant alkaloid that specifically binds topoisomerase I, inhibiting its activity and inducing double stranded breaks in DNA, activating the cell responses to DNA damage and, in response to severe treatments, triggering cell death.<h4>Results</h4>Comparative transcriptomic and proteomic analyses of maize embryos that had been exposed to camptothecin were conducted. Under the conditions used in this study, camptothecin did not induce extensive degradation in the ...[more]