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Metal stress 2


ABSTRACT: Effect of mild metal ion - stress (500µM AlCl3, 500µM VCl3, 1.5mM ZnCl2) on cellular metabolism, resp. on transcription - 30min incubation in yeast Saccharomyces cerevisiae (JSwt - is a FY derivate; MATaleu2ura3trp1HIS3)

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Dagmar Hosiner 

PROVIDER: E-MEXP-2987 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Impact of acute metal stress in Saccharomyces cerevisiae.

Hosiner Dagmar D   Gerber Susanne S   Lichtenberg-Fraté Hella H   Glaser Walter W   Schüller Christoph C   Klipp Edda E  

PloS one 20140109 1


Although considered as essential cofactors for a variety of enzymatic reactions and for important structural and functional roles in cell metabolism, metals at high concentrations are potent toxic pollutants and pose complex biochemical problems for cells. We report results of single dose acute toxicity testing in the model organism S. cerevisiae. The effects of moderate toxic concentrations of 10 different human health relevant metals, Ag(+), Al(3+), As(3+), Cd(2+), Co(2+), Hg(2+), Mn(2+), Ni(2  ...[more]

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