MicroRNAs regulate DC maturation via M-CSFR
Ontology highlight
ABSTRACT: We identify a panel of microRNAs that are differentially expressed during both spontaneous and LPS-induced DC maturation and show the M-CSF receptor (M-CSFR) as a key target for microRNA-mediated regulation. MicroRNA-22, -34a and -155 are up-regulated in mature GM-CSF-generated DC and mediate M-CSFR mRNA and protein down-regulation.
ORGANISM(S): Mus musculus
SUBMITTER: Adri van Oudenaren
PROVIDER: E-MEXP-3311 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA