Ferrous iron sensing in Pseudomonas aeruginosa
Ontology highlight
ABSTRACT:
ORGANISM(S): Pseudomonas aeruginosa
SUBMITTER: Maureen Coleman
PROVIDER: E-MEXP-3459 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
BqsR/BqsS constitute a two-component system that senses extracellular Fe(II) in Pseudomonas aeruginosa.
Kreamer Naomi N K NN Wilks Jessica C JC Marlow Jeffrey J JJ Coleman Maureen L ML Newman Dianne K DK
Journal of bacteriology 20111222 5
Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium best known as the predominant opportunistic pathogen infecting the lungs of cystic fibrosis patients. In this context, it is thought to form biofilms, within which locally reducing and acidic conditions can develop that favor the stability of ferrous iron [Fe(II)]. Because iron is a signal that stimulates biofilm formation, we performed a microarray study to determine whether P. aeruginosa strain PA14 exhibits a specific transcriptio ...[more]
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