Ontology highlight
ABSTRACT:
ORGANISM(S): Burkholderia cenocepacia
SUBMITTER: Heleen Van Acker
PROVIDER: E-MEXP-3532 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Van Acker Heleen H Sass Andrea A Bazzini Silvia S De Roy Karen K Udine Claudia C Messiaen Thomas T Riccardi Giovanna G Boon Nico N Nelis Hans J HJ Mahenthiralingam Eshwar E Coenye Tom T
PloS one 20130313 3
The presence of persister cells has been proposed as a factor in biofilm resilience. In the present study we investigated whether persister cells are present in Burkholderia cepacia complex (Bcc) biofilms, what the molecular basis of antimicrobial tolerance in Bcc persisters is, and how persisters can be eradicated from Bcc biofilms. After treatment of Bcc biofilms with high concentrations of various antibiotics often a small subpopulation survived. To investigate the molecular mechanism of tole ...[more]