Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Hideaki Shimada
PROVIDER: E-MEXP-3734 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fukuzawa Taku T Fukazawa Masanori M Ueda Otoya O Shimada Hideaki H Kito Aki A Kakefuda Mami M Kawase Yosuke Y Wada Naoko A NA Goto Chisato C Fukushima Naoshi N Jishage Kou-Ichi K Honda Kiyofumi K King George L GL Kawabe Yoshiki Y
PloS one 20130225 2
Although excessive fructose intake is epidemiologically linked with dyslipidemia, obesity, and diabetes, the mechanisms regulating plasma fructose are not well known. Cells transfected with sodium/glucose cotransporter 5 (SGLT5), which is expressed exclusively in the kidney, transport fructose in vitro; however, the physiological role of this transporter in fructose metabolism remains unclear. To determine whether SGLT5 functions as a fructose transporter in vivo, we established a line of mice l ...[more]