Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Insulin Receptor-Overexpressing beta-Cells Ameliorate Hyperglycemia in Diabetic Rats through Wnt Signaling Activation


ABSTRACT: To investigate the therapeutic efficacy of beta-cells with IR manipulation, a plasmid containing human IR was stably introduced into rat beta-cell line INS-1 cells (namely, INS-IR cells). In the INS-IR cells, the role of cross-talk between insulin and Wnt signaling pathways in improving the functionality of beta-cells was investigated.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Mi-Hyun Kim 

PROVIDER: E-MEXP-3836 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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