Transcription profiling of brain in three adult humans and three adult chimpanzees
Ontology highlight
ABSTRACT:
ORGANISM(S): Pan troglodytes
SUBMITTER: J.-E. Cheong
PROVIDER: E-MEXP-43 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
DNA sequence and comparative analysis of chimpanzee chromosome 22.
Watanabe H H Fujiyama A A Hattori M M Taylor T D TD Toyoda A A Kuroki Y Y Noguchi H H BenKahla A A Lehrach H H Sudbrak R R Kube M M Taenzer S S Galgoczy P P Platzer M M Scharfe M M Nordsiek G G Blöcker H H Hellmann I I Khaitovich P P Pääbo S S Reinhardt R R Zheng H-J HJ Zhang X-L XL Zhu G-F GF Wang B-F BF Fu G G Ren S-X SX Zhao G-P GP Chen Z Z Lee Y-S YS Cheong J-E JE Choi S-H SH Wu K-M KM Liu T-T TT Hsiao K-J KJ Tsai S-F SF Kim C-G CG OOta S S Kitano T T Kohara Y Y Saitou N N Park H-S HS Wang S-Y SY Yaspo M-L ML Sakaki Y Y
Nature 20040501 6990
Human-chimpanzee comparative genome research is essential for narrowing down genetic changes involved in the acquisition of unique human features, such as highly developed cognitive functions, bipedalism or the use of complex language. Here, we report the high-quality DNA sequence of 33.3 megabases of chimpanzee chromosome 22. By comparing the whole sequence with the human counterpart, chromosome 21, we found that 1.44% of the chromosome consists of single-base substitutions in addition to nearl ...[more]
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