Dataset Information
Transcription profiling of fission yeast cell cycle, cdc25 sep1 block and release
Ontology highlight
ABSTRACT:
ORGANISM(S): Schizosaccharomyces pombe
SUBMITTER: Gabriella Rustici
PROVIDER: E-MEXP-61 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Periodic gene expression program of the fission yeast cell cycle.
Nature genetics 20040613 8
Cell-cycle control of transcription seems to be universal, but little is known about its global conservation and biological significance. We report on the genome-wide transcriptional program of the Schizosaccharomyces pombe cell cycle, identifying 407 periodically expressed genes of which 136 show high-amplitude changes. These genes cluster in four major waves of expression. The forkhead protein Sep1p regulates mitotic genes in the first cluster, including Ace2p, which activates transcription in ...[more]
