Dataset Information
Transcription profiling of fission yeast treated with hydrogen peroxide in fission yeast wild type and csx1 mutant cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Schizosaccharomyces pombe
SUBMITTER: Jürg Bähler
PROVIDER: E-MEXP-176 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.
The EMBO journal 20031201 23
Fission yeast Spc1 (Sty1), a stress-activated mitogen-activated protein kinase (MAPK) homologous to human p38, orchestrates global changes in gene expression in response to diverse forms of cytotoxic stress. This control is partly mediated through Atf1, a transcription factor homologous to human ATF2. How Spc1 controls Atf1, and how the cells tailor gene expression patterns to different forms of stress, are unknown. Here we describe Csx1, a novel protein crucial for survival of oxidative but not ...[more]
