Ontology highlight
ABSTRACT:
INSTRUMENT(S): GenePix 4000B [Axon Instruments]
ORGANISM(S): Yersinia pestis
SUBMITTER: Lance Palmer
PROVIDER: E-MEXP-712 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Grabenstein Jens P JP Fukuto Hana S HS Palmer Lance E LE Bliska James B JB
Infection and immunity 20060701 7
The transcriptional activator PhoP is important for survival of Yersinia pestis in macrophage phagosomes. However, the phagosomes inhabited by Y. pestis have not been well characterized, and the mechanism by which PhoP promotes bacterial survival in these vacuoles is not fully understood. Lysosomal tracers, as well as antibodies to late endosomal or lysosomal proteins, were used in conjunction with confocal or electron microscopy to study the trafficking of phagosomes containing phoP(+) or phoP ...[more]