Dataset Information
Transcription profiling of human peripheral blood monocytes after constitutive adhesion to naive human umbilical vein endothelial cells (HUVEC) to investigate changes in gene expression patterns
Ontology highlight
ABSTRACT:
INSTRUMENT(S): GenePix 4000A [Axon Instruments]
ORGANISM(S): Homo sapiens
SUBMITTER: Thomas Dittmar
PROVIDER: E-MEXP-854 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Alteration in the gene expression pattern of primary monocytes after adhesion to endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 20070319 13
Monocytes originate from precursors made in the bone and remain in the circulation for nearly 24 h. Much effort has been done to identify the molecules regulating transendothelial migration of monocytes during inflammatory conditions. In contrast, considerably less is known about the process of constitutive monocyte emigration although nearly 340 million monocytes leave the circulation each day in healthy individuals. Previous studies indicated that chemokines were up-regulated in monocytes cocu ...[more]
