Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling by array of human non-tumoral Formalin-Fixed Paraffin Embedded colon samples, either positive or negative to diverticulosis


ABSTRACT: Gene expression profiles from anonymous, non-tumoral Formalin-Fixed Paraffin Embedded colon samples, either positive or negative to diverticulosis. Samples were obtained from a Biobank hosted at the Centre Hospitalier Universitaire Vaudois (CHUV), to serve as reference pool for comparison with colon gene expression microarray studies.

ORGANISM(S): Homo sapiens

DISEASE(S): Diverticulosis

SUBMITTER: Mauro Delorenzi 

PROVIDER: E-MTAB-1026 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The recognition that colorectal cancer (CRC) is a heterogeneous disease in terms of clinical behaviour and response to therapy translates into an urgent need for robust molecular disease subclassifiers that can explain this heterogeneity beyond current parameters (MSI, KRAS, BRAF). Attempts to fill this gap are emerging. The Cancer Genome Atlas (TGCA) reported two main CRC groups, based on the incidence and spectrum of mutated genes, and another paper reported an EMT expression signature defined  ...[more]

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