Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Mauro Delorenzi
PROVIDER: E-MTAB-990 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer.
Budinska Eva E Popovici Vlad V Tejpar Sabine S D'Ario Giovanni G Lapique Nicolas N Sikora Katarzyna Otylia KO Di Narzo Antonio Fabio AF Yan Pu P Hodgson John Graeme JG Weinrich Scott S Bosman Fred F Roth Arnaud A Delorenzi Mauro M
The Journal of pathology 20130708 1
The recognition that colorectal cancer (CRC) is a heterogeneous disease in terms of clinical behaviour and response to therapy translates into an urgent need for robust molecular disease subclassifiers that can explain this heterogeneity beyond current parameters (MSI, KRAS, BRAF). Attempts to fill this gap are emerging. The Cancer Genome Atlas (TGCA) reported two main CRC groups, based on the incidence and spectrum of mutated genes, and another paper reported an EMT expression signature defined ...[more]
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