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Epigenetic profiling of Follicular thyroid adenomas and carcinomas using high content DNA methylation arrays

ABSTRACT: While thyroid nodules per se are frequent (4%–50%), thyroid cancer is rare (∼5% of all thyroid nodules). The minimally invasive Fine Needle Aspiration Cytology (FNAC) is the current gold standard for the diagnosis thyroid nodule malignancy. However, proper discrimination of follicular neoplasias often require more invasive diagnostic techniques. To develop a novel molecular classification system for thyroid cancer malignancy, we performed a genome-wide epigenetic profiling of 54 fresh frozen Follicular like thyroid samples using the Illumina Human DNA Methylation EPIC platform.

ORGANISM(S): Homo sapiens

SUBMITTER: Juan Ramón Tejedor

PROVIDER: E-MTAB-10906 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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